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摘要
摘要
A highly infectious, deadly virus from the central African rain forest suddenly appears in the suburbs of Washington, D.C. There is no cure. In a few days 90 percent of its victims are dead. A secret military SWAT team of soldiers and scientists is mobilized to stop the outbreak of this exotic "hot" virus.The Hot Zonetells this dramatic story, giving a hair-raising account of the appearance of rare and lethal viruses and their "crashes" into the human race. Shocking, frightening, and impossible to ignore,The Hot Zoneproves that truth really is scarier than fiction. From the Paperback edition.
评论 (6)
出版社周刊评论
Far more infectious than AIDS, filoviruses (thread viruses) are relentless killer machines that consume a human body in days, causing a gruesome death. Symptoms include liquefying flesh, spurts of blood, black vomit and brain sludge. Outbreaks of the Ebola filovirus devasted Sudan and Zaire in 1976. And in 1989 Philippine monkeys in a Reston, Va., research lab, found to be infected with Ebola, were the target of a U.S. Army-led biohazard task force that decontaminated the lab, exterminating hundreds of monkeys to prevent the possible airborne spread of the disease to humans. In a horrifying and riveting report, portions of which appeared in the New Yorker , Preston ( American Steel ) exposes a real-life nightmare potentially as lethal as the fictive runaway germs in Michael Crichton's The Andromeda Strain. Preston plausibly argues that the emergence of AIDS, Ebola and other highly adaptable rain-forest viruses is a consequence of ecological ruin of the tropics. A movie based on this book, directed by Ridley Scott ( Alien ), will star Robert Redford. Author tour. (Sept.) (c) Copyright PWxyz, LLC. All rights reserved
《书目》(Booklist)书评
One of the nation's more famous planned communities, Reston, Virginia, stands at the epicenter of this whirlwind tale of potential biological disaster. Preston, award-winning author of First Light (1987) and American Steel (1991), wrote a 1992 New Yorker article on the recognition and containment of a devastating tropical filovirus at a monkey house--the Reston Primate Quarantine Unit--operated by a division of Corning, Inc., about 10 miles from Washington, D.C. Preston expands on that article by describing his 1993 journey to Kitum Cave on Mount Elgon near the edge of the Rift Valley in Kenya, the place scientists believe is the source of all four identified filoviruses: the Marburg, the Sudan, the Zaire, and the Reston strains of Ebola. The Hot Zone is a compelling "science fact" thriller: filoviruses kill most of their monkey and human hosts in vividly gruesome ways. The process through which the U.S. Veterinary Corps at Frederick, Maryland, spotted Ebola at Reston and recruited a secret SWAT team to contain it is tense and terrifying; and Preston, who lived in Kenya for part of his youth, places this chilling incident in a broad global context, eloquently arguing that "the emergence of AIDS, Ebola, and any number of other rain-forest agents [may be] a natural consequence of the ruin of the tropical biosphere." Expect reader interest: Random House plans heavy promotion; Robert Redford and Jodie Foster are working on a motion picture based on Preston's article; and Dustin Hoffman stars in a second film on this frightening subject. ~--Mary Carroll
Choice 评论
With this account of the emergence of the Ebola virus from the depths of Africa to a suburb of Washington, DC, Preston demonstrates that reality is far more intriguing and of greater personal impact than is fiction. This is the history of the rise of a new viral disease with a high mortality rate and the organization of the resources available to deal with the problem. The action and events reported describe the efforts to coordinate available resources, such as highly developed medical technology, an exceptionally well-educated and trained medical community, the Center for Disease Control in Atlanta, and facilities of the US Army necessary to develop a methodology in situ to deal with a potential public health disaster. Once the reader begins to turn the page, it is hard to put the book aside. The author has a well-timed sense of presentation that provides more suspense than many a mystery or horror story. The personalities involved in the project are brought into the reader's world, as well as the recognition that such an event could actually happen and is not something confined to science fiction. More importantly, one should note that the conditions for such an event are and have always been present: one does not need space travel or gene splicing. In the end, the reader learns that despite all progress and understanding, nature is still running the show. Not a technical book; it is directed to the general reader who wishes to be informed and aware. Recommended. General. A. D. Gounaris; emerita, Vassar College
《学校图书馆杂志》(School Library Journal)书评
YAWarningnot for faint hearts or weak stomachs! In 1989, an obscure filovirus travels from the African rain forest to a lab near Washington, D.C., where the monkeys quickly sicken and die. Preston traces the history of the Warburg and Ebola filoviruses in minute, horrific detail that is as fascinating to read as it is alarming to contemplatethese filoviruses have the capability to mutate and possibly cross species. There are extraneous descriptions of scenery and of the characters' lives, but these passages serve to relieve the mounting tension and terror as the virus spreads and the CDC, the Army, and a private firm work out a containment plan to prevent a mass epidemic. YAs interested in science or fans of Stephen King or Michael Crichton will find this a fast-paced medical chiller right to the last disturbing page.Judy Sokoll, Fairfax County Public Library, VA (c) Copyright 2010. Library Journals LLC, a wholly owned subsidiary of Media Source, Inc. No redistribution permitted.
Kirkus评论
A bone-chilling account of a close encounter with a lethal virus, by New Yorker writer Preston (American Steel, 1991). The African rain forests from which HIV emerged are home to other viruses that make AIDS seem like child's play. Preston opens with a disturbingly graphic description of the meltdown of a human body invaded by a filovirus. Essentially, the body liquefies, spilling out billions of copies of the deadly virus, which can trigger an explosive chain of lethal transmission. Only micro-outbreaks have occurred so far, but the potential exists for worldwide catastrophe. In the fall of 1989, a monkey- importing company with a primate quarantine unit in Reston, Va. (about ten miles from Washington, D.C.), noted that its monkeys were dying off at an alarming rate and with suspicious symptoms. When the cause was found to be Ebola, a particularly deadly filovirus, all hell broke loose. The US Army quickly took over, and a SWAT team was sent in to halt the spread of the virus. The complicated and hazardous job required the donning of biological space suits, entering the monkey house (the ``hot zone''), killing each monkey, and retrieving tissue samples. A major portion of the book is about this operation, which had to be conducted in secret, since public awareness could easily have meant widespread panic. Preston is adept at telling the story through the voices of the participants, who become very real (he employs pseudonyms only twice). That the virus, now known as Ebola Reston, turned out not to affect humans is small comfort: Viruses mutate rapidly, and the rain forests are only a plane ride away. A totally convincing page turner, proving that truth is scarier than fiction. Portions of this biomedical thriller appeared in the New Yorker in somewhat different form; it will be made into a movie starring Robert Redford and directed by Ridley Scott (Alien). (Author tour)
《图书馆杂志》(Library Journal )书评
Preston argues that dangerous viruses like HIV have emerged with the destruction of jungles and rain forests. Excerpted in The New Yorker in late 1992. (c) Copyright 2010. Library Journals LLC, a wholly owned subsidiary of Media Source, Inc. No redistribution permitted.
目录
Part 1 The Shadow of Mount Elgon | p. 1 |
Part 2 The Monkey House | p. 155 |
Part 3 Smashdown | p. 283 |
Part 4 Kitum Cave | p. 373 |
Main Characters | p. 412 |
Glossary | p. 414 |
Credits | p. 419 |