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Summary
Summary
Completely revised and updated, the 3rd Edition of this excellent resource delivers the guidance needed to select, perform, and evaluate the results of laboratory tests more effectively. This comprehensive reference bridges the gap between the clinical laboratory and medical management by relating pathophysiology to analytical results in health and disease. New topics include cytokines, cardiac function, organ transplantation and management principles.
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Doody's Book Review
This is the third edition of what is considered by many to be the standard reference work in the field of clinical chemistry. The previous edition was published in 1994. This edition is intended to be the most authoritative and current source of information pertaining to clinical chemistry. Since clinical chemistry is a discipline that is continually changing, timely revisions of major reference works are both necessary and valuable. This book is intended to serve as a comprehensive reference for students, residents, and practitioners alike. It is a bit too detailed for day-to-day use in the clinical chemistry portion of a medical technology curriculum. However, it is a "must-have" reference for clinical chemists and clinical pathologists and it should be available in the workplace for use by medical technologists and clinical pathology residents. It will also be a useful reference for laboratory-oriented practitioners in many medical specialties. The 50 chapters are divided into six sections. Compared to the previous edition, this edition contains seven new chapters that cover important emerging areas practice including laboratory management, organ transplantation, cytokines, and bone metabolism. Chapters that appeared in the second edition have been extensively revised to incorporate new material. The new edition contains 3000 more literature citations than the previous edition with most of the new references published between 1995 and 1997. The last chapter of the book is a compendium of useful information that includes conversion factors, constants, compositions of buffer solutions, nomograms, and reference values. As was the case for previous editions, this third edition is distinguished from most other clinical chemistry books in that it strikes just the right balance between the theoretical and clinical aspects of a topic and the technical and practical aspects of analytical approaches and test methodologies. The editors are recognized as leaders in the field, and the contributors to the various chapters are authorities both in their areas of practice and in clinical chemistry education and training. This third edition continues to set a high standard for practice-oriented reference works in the field of clinical chemistry. Earle W. Holmes, PhD(Loyola University Medical Center). Copyright 2001, Doody Publishing
Table of Contents
| Part I Laboratory Principles |
| General Laboratory Techniques and Procedures |
| Specimen Collection and Processing, Sources of Biological Variation. |
| Part II Analytical Techniques and Instrumentation |
| Spectrophotometric Techniques |
| Fluorometry, Nephelometry, And Turbidimetry |
| Basic Principles of Radioactivity and Its Measurement |
| Electrochemistry |
| Electrophoresis |
| Chromatography/Mass Spectrometry |
| Principlesof Immunochemical Techniques |
| Automation in the Clinical Laboratory. |
| Part III Chemometrics |
| Statistical Procedures |
| Selection and Interpretation of Laboratory Procedures |
| Selection and Evaluation of Methods |
| Establishment and Use of Reference Values. |
| Part IV Laboratory Management |
| Clinical Laboratory Informatics |
| Laboratory Management |
| Quality Management. |
| Part V Analytes |
| Nucleic Acid Biochemistry and Diagnostic Applications |
| Amino Acids |
| Proteins |
| Cytokines |
| Clinical Enzymology |
| Tumour Markers |
| Carbohydrates |
| Lipids, Lipoproteins, And Apolipoproteins |
| Therapeutic Drug Monitoring |
| Clinical Toxicology |
| Toxic Metals |
| Vitamins |
| Trace Elements |
| Electrolytes and Blood Gases. |
| Part VI Pathophysiology |
| Physiology and Disorders of Wates, Electrolyte, And Acid-Base Metabolism |
| Liver Function |
| Cardiac Function |
| Renal Function and Nitrogen Metabolics |
| Gastric, Pancreatic, And Intestinal Function |
| Organ Transplantation |
| Nutritional Assessment, Therapy, And Monitoring |
| Mineral and Bone Metabolism |
| General Endocrine Function |
| Pituitary Function |
| Thyroid Function |
| Function of the Adrenal Cortex |
| Cathecol Amines and Serotonin |
| Reproductive Endocrine Function |
| Biochemical Aspects of Hematology |
| Porphyrins and Disorders of Porphyrin Metabolism |
| Clinical Chemistry of Pregnancy |
| Lysosomal Storage Disease |
| Appendix |